Current Clinical Trials Underway
Currently, two Phase I human clinical trials are underway. The trials are being conducted by Roche Laboratories and Balance Therapeutics. Both trials are investigating compounds that are shown to restore more balanced neuro-transmission, and improved learning, in mouse models.
A multi-center, randomized, double-blind, placebo-controlled, multiple dose study to investigate safety and tolerability of RG1662 in individuals with Down Syndrome. Specific information about this trial may be found on the Roche Clinical Trial Protocal Registry.
Locations and Contacts of Roche Trial of Trial Investigators can be found here.
BTD-001 DS102: A Phase 1b, Double-blind, Randomized, Placebo-Controlled, Parallel Group Study of the Safety, Tolerability, Preliminary Efficacy and Pharmacodynamics of BTD-001 in Young Adults and Adolescents with Down Syndrome.
A National Down Syndrome Patient Registry
The NIH announced on October 20 that the contract has been awarded to establish a new Down Syndrome Patient Registry. The registry will allow people with Down syndrome or their family members to enter contact information and health history into a secure, on-line database. This will facilitate connections between individuals with Down syndrome and researchers. Details of the registry may be found here.